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Department of Biotechnology, Anna University

Home      Faculty
Department of Biotechnology Anna University

Dr. Sangita Venkataraman


UGC - Assistant Professor, FRP

Department of Biotechnology,

Anna University, Chennai 600025
   Vidwan id: 275228

044 22358360

sangita.venkataraman@gmail.com




Education         Experience        





Education

Degree Major Subject Studied Institution Year
Ph. D. Thesis title:X-ray diffractionstudies on the coat protein mutants of Sesbania mosaic virus Indian Institute of Science, Bengaluru. 2005
Integrated M.Sc. Life Science Bharathidasan University, Tiruchirapalli, India 2000
Advanced Diploma Software Engineering Aptech Computer Education, Tiruchirapalli 1999

Professional Experience

Department of Biotechnology, Anna University, Chennai: UGC-Assistant Professor, (Mar 2021 – Current). Teaching: Concepts in Computational Biology to M.Tech. Research: Completed DST-SERB project on “Structural studies on Banana Bunchy Top Virus from India” for 33 lakhs.
Department of Biotechnology, Acharya Nagarjuna University, Guntur: UGC-Assistant Professor, (Dec 2017 – Current). Teaching: Molecular Biology, Genetic Engineering and Plant Biotechnology to M.Tech. and M.Sc. students. Research: DST-SERB grant on “Structural studies on Banana Bunchy Top Virus from India” for 33 lakhs, Completed Orientation Course at Madras University, Oct-Nov, 2019 with A grade.
Amity Institute of Integrative Sciences & Health (AIISH), Amity University Haryana; Associate Professor, (Dec 2015 – Dec 2017). Teaching: Advanced Molecular Biology, MolecularBiology, Genomics & Proteomics for B.Sc., B.Tech. and M.Sc. students. Research: DST-SERB grant on Structural studies on Banana Bunchy Top Virus from India for 33 lakhs. Administration: Member Internal ethical committee, FIST-Project implementation committee, Cultural committee, Mentor B.Sc Biotechnology.
MGM’s Institute of Biosciences and Technology, Aurangabad; Associate Professor,(Feb 2014 - Dec 2014). Teaching: Virology, Principles of Gene Manipulation & Genomics, GeneticEngineering, Cell Biology and RDT for B.Sc. and M.Sc. students. Administration: NAAC Coordinator during the first cycle of assessment for the Institute for which the Institute was graded with a B (Score 2.55), Time tableincharge, PG coordinator, member of Research and ethics committee, Grievances & Redressal committee, Vishakha committee, Internal syllabus committee.
Dr. DY Patil Biotechnology and Bioinformatics Institute, Pune, India; Assistant Professor, (Oct 2012 - Jan 2014). Teaching: Molecular Biology of Viruses, r-DNA Technology, GeneticEngineering, Cell Biology and Genomics for B.Tech, M.Tech and M.Sc students. Administration: Member of Board of Studies, Recognized Research Guide, Member of Parent-Teachers Association, Cultural Committee etc., Member of the organizing committee of International Conference on Advances in Biotechnology and Bioinformatics.
University of California San Diego, CA, USA; Postdoctoral Researcher, (Dec 2008 – May2010). Research: Design and development of a fully customized database and an interactivewebsitefor archiving and analysis of transcriptomic data related to doping from labs sponsored by World Anti Doping Agency (WADA) (http://www.wadainformatics.org/).
The Scripps Research Institute, CA, USA; Postdoctoral Researcher, (Feb 2007 - Dec 2008). Research: Elucidation and analyses of three-dimensional crystal structures of oncolyticpicornaviruses, Elucidation of three-dimensional crystal structure of Fiber knob proteins of subgroup B Adenoviruses, Development of VIPERdb, a relational database and web site for icosahedral virus structures and their analysis (http://viperdb.scripps.edu/).
Helix Genomics Pvt. Ltd., Hyderabad, India; Scientist, (Nov 2005 - Oct 2006). Responsibilities: Project training for B.Tech, M.Tech and M.Sc students, development of modulesfor biological softwares.


Honors, achievement and awards

Best poster award at International Conference on Banana-2020
Early Career Award of 35 lakh from DST-SERB (Structural studies on Banana Bunchy Top Virus from India (2016)
Bursary award from DST for participation in 24th Congress & General Assembly of the International Union of Crystallography 2017 from 21 – 28 August 2017, Hyderabad, India
Selected for DS Kothari Postdoctoral Fellowship (2012)
Qualified Graduate Aptitude Test in Engineering (GATE) in year 2000.
Awarded Junior Research Fellowship (JRF) and Senior Research Fellowship (SRF) by UGCCSIR, Ministry of Human Resource Development, Government of India (2000).




Research      Projects





Area of Research


• Macromolecular Crystallography

• Structural Virology

• Integrative Sciences & Omics Technologies



Research Guideship


• Dr.D.Y.Patil Biotechnology and Bioinformatics Institute, Pune

• Amity University Haryana



Projects Mentored for Post Graduate students


• In silico analysis of the proteins involved in cellular signaling in human.

• Homology Modelling of the proteins from Banana Bunchy Top Virus.

• In silico analysis of RNA dependent RNA polymerase from viruses.

• Role of protein-protein interactions in the assembly of viral capsids.

• Structural insights into the role of inter-subunit interactions in the Assembly of Viruses. ●Studies on the composition of Coding and Non-Coding Regions in completely annotated Mycobacterium Species.

• Structure function studies on Alcohol Dehydrogenase.

• Structure function studies on Androgen Receptor Protein.



Membership(s)


• Indian Crystallographic Association (Life Member)


Workshops


• Workshop on Molecular Docking, Virtual Screening & Computational Biology using Schrodinger Biologics Suite, AUH, Jan 23 -26, 2017.

• Workshop on NGS data analysis, MGM’s IBT, Feb 28-Mar 5, 2014.

• Workshop on Advanced Topics in EM Structure Determination, Center for Integrative Molecular Biosciences, The Scripps Research Institute, La Jolla, CA. Nov 10-16, 2007. Poster: “Structure ofSeneca Valley Virus -001: an oncolytic picornavirus representing a new genus”)

• Workshop on Cryo-EM, Molecular Biophysics Unit, Indian Institute of Science, Bangalore. May 2023, 2005.



Publications         Conferences        





Publications


  • Mariya Rashid, Shubham Mittal, Sangita Venkataraman*. (2020) Analysis of host protein interactions in plant viruses: an in silico study using Sesbania mosaic virus. Virus Genes 56:756-766, DOI10.1007/s11262-020-01794-w
  • Sundaram S, Selvarajan R, Savithri HS, Sangita Venkataraman*. (2020) Towards understanding the structure of the capsid of Banana bunchy top virus. BioRxiv. doi: https://doi.org/10.1101/2020.02.12.945212
  • Sangita Venkataraman, Ramasamy Selvarajan (2019). Recent advances in understanding thereplication initiator protein of the ssDNA plant viruses of the family Nanoviridae. Virus Disease. https://doi.org/10.1007/s13337-019-00514-9
  • S. KundhavaiNatchiar, Sangita Venkataraman, Tina-Marie Mullen, Glen R. Nemerow, Vijay S. Reddy (2018). Revised Crystal Structure of Human Adenovirus Reveals the Limits on Protein IX QuasiEquivalence and on Analyzing Large Macromolecular Complexes. J Mol. Biol. 430 (21), 4132-4141
  • Sangita Venkataraman*, Burra VLS Prasad, Ramasamy Selvarajan* (2018). RNA dependentRNA Polymerases: Insights from structure, function, and evolution. Viruses, 10(2), 76; doi:10.3390/v10020076
  • S. Venkataraman, S. Sundaram, R. Selvarajan and H. S. Savithri. Structural studies on banana bunchy top virus. Acta Cryst. (2017). A73, C1188 (Conference publication)
  • Carrillo-Tripp M, Shepherd CM, Borelli IA, Venkataraman S, Lander G, Natarajan P, Johnson JE, Brooks CL 3rdand Reddy VS (2009). VIPERdb2: an enhanced and web API enabled relational database for structural virology. Nucl. Acid Res., 37: D436-D442.Venkataraman S, Reddy SP, Loo J, Idamakanti N, Hallenbeck PL, Reddy VS (2008). Structure of Seneca Valley Virus-001: an oncolytic picornavirus representing a new genus. Structure, 16(10):1555-1561.
  • Pache L, Venkataraman S, Reddy VS and Nemerow GR (2008). Structural Variations in Species B Adenovirus Fibers Impact CD46 Association. J Virol, 82(16):7923-7931.
  • Venkataraman S, Reddy SP, Loo J, Idamakanti N, Hallenbeck PL and Reddy VS (2008).Crystallization and preliminary X-ray diffraction studies of Seneca Valley Virus-001, a new member of the Picornaviridae family. Acta Cryst, F64:293-296.
  • Pache L, Venkataraman S,Nemerow GR, Reddy VS (2008). Conservation of fiber structure and CD46 usage by subgroup B2 adenoviruses. Virology, 375:573-579. (Cover Page)
  • Sangita V, Satheshkumar PS, Savithri HS, Murthy MR (2005). Structure of a mutant T = 1capsid of Sesbania mosaic virus: role of water molecules in capsid architecture and integrity. ActaCryst., D61:14061412.
  • Sangita V, Lokesh GL, Satheshkumar PS, Saravanan V, Vijay CS, Savithri HS, Murthy MR(2005). Structural studies on recombinant T = 3 capsids of Sesbania mosaic virus coat protein mutants. Acta Cryst., D61:1402-1405.
  • Satheshkumar PS, Lokesh GL, Sangita V, Saravanan V, Vijay CS, Murthy MR and Savithri HS (2004). Role of metal ion-mediated interactions in the assembly and stability of Sesbania mosaic virus T=3 and T=1 capsids. J Mol. Biol, 342:1001-1014.
  • Sangita V, Lokesh GL, Satheshkumar PS, Vijay CS, Saravanan V, Savithri HS, Murthy MR(2004). T=1 capsid structures of Sesbania mosaic virus coat protein mutants: determinants of T=3 and T=1 capsid assembly. J Mol Biol, 342:987-999.
  • Sangita V, Parthasarathy S, Toma S, Lokesh GL, Gowri TDS, Satheshkumar PS, Savithri HS andMurthy MRN (2002). Determination of the structure of the recombinant T=1 capsid of sesbania mosaic virus. Curr. Sci., 82:1123-1131 (Cover Page).


Book Chapters

1. Sangita Venkataraman*, SM Paul Khurana, Vijay S Reddy, (2020) “Biomedical Applications of Viral Nanoparticles in Vaccine Therapy”, NanoBioMedicine, Springer Singapore, Feb 2020, 213-236. ISBN 978 -981-329-897-2. https://doi.org/10.1007/978-981-32-9898-9.

2. Sangita Venkataraman*, HS Savithri, MRN Murthy, (2018) “Structural Aspects of Plant Viruses”, Plant Viruses: Diversity, Interaction and Management, CRC Press, Feb 2018, ISBN 9781138061514 (*Corresponding Author)



Conference(s) Organized


  • One Day Conference on Trends and Prospects of Biomedical and Biotechnology research in the innovation Decade” on 31 st July 2014 at Rukmini Auditorium, MGM Hospital Campus, Aurangabad.
  • National Symposium on “Lipids in the forefront: A lot more to Discover”, Amity University Haryana, Dec 14 -15, 2016.
  • One day seminar on “Current Trends and Recent Advances in Structural Biology”, Amity University Haryana, April, 2016


Conferences Participated


  • International Conference on Banana – 2020. ICAR-National Research Centre for Banana, Tiruchirapalli. 22 -25 February, 2020. (Best Poster Award: Structural studies on coat protein of Banana Bunchy Top Virus”)
  • 5thNational Asian PGPR Conference for Sustainable and Organic Agriculture Eco-friendly BioInnovations for Integrated Crop Management, Soil Health and Environment. Acharya Nagarjuna University, Guntur -522510, 23rd -25th February 2019. (Poster: “Structural studies on coat protein of Banana Bunchy Top Virus”)
  • Consultative workshop on “NaiTalim, Experiential Learning and Work Education in Higher Education Curriculum”, Acharya Nagarjuna University, Guntur -522510, 01-10-2018.
  • National Workshop on Regulatory Mechanisms, Transgenic Technology and Applications in Plants ( RMTTAP), Acharya Nagarjuna University, Guntur – 522510, 2nd – 3rd August 2018
  • International Conference on Intrinsically Disordered Proteins: Forms, Functions and Diseases, IISER, Mohali, 9th-12th December 2017 (Poster: “Intrinsic Disorder in Signaling Proteins”)
  • VIROCON 2017, Nitte University, Mangalore, 7-9 December 2017. (Oral: “Structural studies on coat protein of Banana Bunchy Top Virus”)
  • 24th Congress & General Assembly of the International Union of Crystallography 2017, Hyderabad convention center, 21 -28 August 2017. (Poster: “Structural studies on Banana Bunchy Top Virus”)
  • Symposium on New Directions in Cell Signaling, Amity University Haryana, Apr 21, 2017.
  • National symposium on “Multidrug Resistant Tuberculosis: Challenges & Strategies”, Amity University Haryana, Apr 20, 2017.
  • International Conference on Drug Design 2017, Jawaharlal Nehru University, New Delhi, Apr 7-9, 2017. ( Poster: “In silico study of host-virus interactions using Sesbania mosaic virus”)
  • National Conference on Molecular Insights in Genetics and Biotechnology-Emerging Trends and Futu re Prospects, Osmania University, Feb 27-28, 2017. Invited Speaker
  • National Symposium on “Lipids in the forefront: A lot more to Discover”, Amity University Haryana, Dec 14 -15, 2016.
  • 8th International Geminivirus Symposium & the 6th International ssDNA Comparative Virology Workshop, Taj Vivanta, New Delhi & Jawaharlal Nehru University, Nov 7 -10, 2016.
  • New Horizons in Biotechnology, Indian Institute of Science, Bengaluru, June, 2016.
  • International Conference on Translational Medicine and Stem Cell Research, Amity University Haryana, Feb 5 -6, 2016.
  • International Conference on Biotechnology and Bioinformatics, Yashada, Pune. Feb 6-8, 2015. ( Poster: “In silicoanalysis of RNA dependent RNA polymerases from viruses”)
  • International Conference on Advances in Biotechnology and Bioinformatics, Le Meridian, Pune. Nov 25 -27, 2013. (Poster: “Structure analysis of isometric plant viruses.”)
  • XXXIII National Seminar on Crystallography. NCL, Pune, India. Jan 8-10, 2004. (Poster: “Structure of T=1 capsids of Sesbania mosaic virus coat protein deletion mutants: implications onassembly ”)
  • XXXII National Seminar on Crystallography. University of Jammu, Jammu Tawi, India. Oct 24-26, 2002. (Poster: “Determination of the structure of the recombinant T=1 capsid of sesbania mosaicvirus.”)

Referees


  • Prof. M. R. N. Murthy, Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012. Tel: 080-23372981 Email: mrn@iisc.ac.in
  • Vijay Reddy, Ph.D., Department of Molecular Biology, TPC6, The Scripps ResearchInstitute, 10550 N Torrey Pines Road. La Jolla, CA 92037. Tel: 858-784-8191 Email: reddyv@scripps.edu
  • Prof. H. S. Savithri, Department of Biochemistry, Indian Institute of Science, Bangalore 560012. Tel: 91-80-22932473 Email: hss@alumni.iisc.ac.in


Contact





Contact


UGC - Assistant Professor, FRP, Department of Biotechnology,

Anna University, Chennai 600025

sangita.venkataraman@gmail.com

044 22358360