The major thrust areas in Research
Recombinant protein expression
• Creating an ideal plant platform for the expression of recombinant diagnostic and prophylactic proteins
• Find out the factors regulating transgene integration and expression
• Interaction between transgene and plant metabolism
• Overexpression and purification of nutraceuticals from plants
• Pathway modification
Plant tissue culture
• Clonal propagation of endangered and red book listed medicinal plants and isolation of medicinally important compounds from them
•Analysis of antioxidant activity of traditional medicinal plants
• Number of M.E./ M.Tech. Projects Guided : 19
• Number of M.E./ M.Tech. Projects Guiding : 6
Sponsored Projects Completed
• “Development of plant expression system for the production of recombinant therapeutic proteins" (November-2010 - December-2013). Project Cost: 21.00.
Research Papers Published in International Journals
- A.K.Gupta, N.Anoop,A.Mushtaq, V.Mathangi, "Transgenic legumes a mini review", JPAS, published by Premier Publishers. Vol. 1, pp. 27-34 (1999).
- Jeeva Jothi D , Mathangi Ganapathy, "Hepatoprotective effect of Cassia auriculata L Leaf Extracts On Carbon Tetra Chloride Intoxicated Liver Damage in Wistar Albino Rats", Asian Journal of Biochemistry, published by Academic Journals. Vol. 6, Issue 1, pp. 104-112 (2011).
- Mathangi Ganapathy • Adhiseshan Perumal • Chakravarthi Mohan • Harunipriya Palaniswamy Kaliraj Perumal, "Immunogenicity of Brugia malayi Abundant Larval Transcript-2, a potential filarial vaccine candidate expressed in tobacco", Plant Cell Reports, published by Springer. Vol.33, pp. 179--188 (2014).
- Mathangi Ganapathy, M. Chakravarthi , S. Jason Charles, P. Harunipriya,S. Jaiganesh, N.Subramonian & P. Kaliraj, " Immunodiagnostic Properties of Wucheraria bancrofti SXP-1, a Potential Filarial Diagnostic Candidate Expressed in Tobacco Plant, Nicotiana tabacum", Applied Biochemistry and Biotechnology, published by Springer. Vol. 76, pp. 1889-1903(2015).
- Mathangi Ganapathy, Swathi Bhunia, " Neutraceuticals, the new generation therapeutics", Advanced Techniques in Biology and Medicine, published by e-science central open access.Vol. 4, Issue 2, pp. 1-5 (2016)
- Mathangi Ganapathy, "Plants as Bioreactors", Advanced Techniques in Biology and Medicine, published by E-science central open access. Vol. 4, Issue 1, (2016).
- Rukmani Thiruppathy, Sachin Mishra, Mathangi Ganapathy, Parasuraman Padmanabhan Balazs Gulyas, "Nanoparticle functionalization and its potential for molecular imaging ", Advanced Science, published by Wiley VCH. Vol. 4, (2017)
- Mathangi Ganapathy, Perumal Kaliraj, "Production of recombinant proteins from plants- an overview", Advances in biotechnology E BOOK ,Chapter 5, published by open access e books.pp. ISBN 978-81-935757-0-3. (2017)
Research Papers Published in National Journals
- V.Mathangi, A.K.Gupta, "Genetic manipulation of the plant cell", Biology Education , (1993).