Prof. P. Kaliraj

RESEARCH AND DEVELOPMENT ACTIVITIES

• Ph.D. 37 Degree Awarded, (Submitted thesis - 3, Ongoing -3)

• M.S/M.Tech and B.Tech. 70 Dissertations

• Patents Filed 3

• Products Commercialized 1

• Products Developed 2

• Publications 69 (International 58, National 11)

• Scientific abstracts/Proceedings in conference 70 (International 20, National 50)

• Book Chief Editor and contributing author Vol 7 Biotechnology (Science and Technology Encyclopedia series, Tamil version)

Research Publications in accredited journals

• Paul R, Sandeep J, Mahalakshmi N, Kaliraj P. Elucidation of Immunological response and its Regulatory Network by P-TUFT-ALT-2: A Promising Fusion Protein Vaccine for Human Lymphatic Filariasis. Royal Society Open Science, 2018. Accepted (Impact Factor: 2.243)
• Jason Charles, Mahalakshmi N, Desai PK, Kaliraj P. Enhancing the sensitivity of ELISA using monoclonal and polyclonal antibodies to rWbSXP1 antigen. Research Journal of Biotechnology, 2017. (Impact factor: 0.29)
• Paul R, Saha G, Selvaraja V, Kaliraj P. Cloning, expression and characterization of Brugia malayi abundant larval protein Transcript-2 (BmALT-2) expressed in Pichia pastoris. Biotechnology & Biotechnological Equipment. 2017, 31 (2) (Impact factor: 1.059)
• Christiana I, Aparnaa R, Rohit R, Rao DN, Kaliraj P. Effect of muramyl dipeptide and alum adjuvants on immunization with Filarial multi-antigen peptide vaccine in mice model. Helminthologia. 2016, 53(3) (Impact factor: 0.472)
• Ravishankaran, Shridharan RN, Vishal LA, Karande AA, Kaliraj P. Evaluation of immunediagnostic assay for the exposure of stage specific filarial infection. Acta Parasitologica. 2016, 61(2) (Impact factor: 1.13)
• Madhumathi J, Prince PR, Rao DN, Reddy MVR, Kaliraj P. Epitope mapping of Brugia malayi ALT2 and the development of a multiepitope vaccine for lymphatic filariasis. Journal of Helminthology, 91(1), 2016 (Impact factor: 1.42)
• Kamatchi R, Charumathi J, Ravishankaran R, Kaliraj P, Meenakshi sundaram S. Construction and bacterial expression of a recombinant singlechain antibody fragment against Wuchereria bancrofti SXP1 antigen for the diagnosis of lymphatic filariasis. Journal of Helminthology. 2016, 90(1) (Impact factor: 1.42)
• Anugraha G, Madhumathi J, Prince PR, Reddy MVR, Kaliraj P. Chimeric epitope vaccine from multistage antigens for lymphatic filariasis. Scandinavian Journal of Immunology. 2015, 82(4) (Impact factor: 2.256)
• Ganapathy M, Chakravarthi M, Charles SJ, Subramonian, N, Kaliraj P. Immunodiagnostic Properties of Wucheraria bancrofti SXP1, a Potential Filarial Diagnostic Candidate Expressed in Tobacco Plant, Nicotiana tabacum. Applied Biochemistry and Biotechnology. 2015, 176(7) (Impact factor: 1.413)
• Ramanathan A, Immanuel C, Rao DN, Kaliraj P. Dissecting the immune response elicited by WbALT2, ALT MAP in clinical populations and mouse model: a prophylactic measure against lymphatic filariasis. Lymphatic Research and Biology. 2015, 13(2) (Impact factor: 1.552)
• Ravishankaran R, Radhika NS, Ansel Vishal L, Karande AA, Kaliraj P. An evaluation of antigen capture assays for detecting active filarial antigens. Journal of Helminthology. 2015, 89(3) (Impact factor: 1.42)
• Anugraha G, Madhumathi J, Jeya Prita PJ and Kaliraj P. Biodegradable poly-l-lactide based microparticles as controlled release delivery system for filarial vaccine candidate antigens. European Journal of Pharmacology. 2015, 747: 174-180 (Impact Factor: 2.68).
• Malathi B, Mona S, Thiyagarajan D and Kaliraj P. Immunopotentiating nano-chitosan as potent vaccine carter for efficacious prophylaxis of filarial antigens. International Journal of Biological Macromolecules. 2015, 73:131-137 (Impact Factor: 3.10)
• Ansel Vishal L, Nazeer Y, Ravishankaran R, Mahalakshmi N and Kaliraj P. Evaluation of Rapid Blood Sample Collection in the Detection of Circulating Filarial Antigens for Epidemiological Survey by rWbSXP-1 Capture Assay. PLoS ONE. 2014, 9(7): e102260 (Impact Factor: 3.534)
• Jawaharlal JP, Madhumathi J, Prince RP and Kaliraj P. Repeat region of Brugia malayi sheath protein (Shp-1) carries Dominant B epitopes recognized in filarial endemic population. Acta Parasitologica. 2014, 59 (3): 454-458 (Impact Factor: 1.144)
• Natarajan Mahalakshmi, Aparnaa Ramanathan and Kaliraj P. Evaluation of immune response elicited by inulin as an adjuvant with filarial antigens in mice model. Scandinavian Journal of Immunology. 2014, 80(4): 261-270 (Impact Factor: 2.199)
• Sakthidevi M, Hoti SL and Kaliraj P. Functional analysis of a highly conserved abundant larval transcript-2 (alt-2) intron 2 repeat region of lymphatic filarial parasites. Infection, Genetics & Evolution. 2014, 24: 177-182 (Impact Factor: 3.264)
• Aparnaa R, Mahalakshmi N, Harini A, Jeyaprita PJ, Anugraha G, Amdare NP, Khatri VK, Reddy MV and Kaliraj P. Wuchereria bancrofti 20/22 a homologue of abundant larval transcript L3 stage filarial antigen: molecular and immunological characterization. Parasite Immunology. 2014, 36 (10): 475- 484 (Impact Factor: 1.849)
• Ravishankaran R, Radhika NS, Vishal LA, Meenakshisundaram S, Karande AA and Kaliraj P. An evaluation of antigen capture assays for detecting active filarial antigens. Journal of Helminthology. 2014, 2: 1-7 (Impact Factor: 1.303)
• Jeya Prita Parasurama Jawaharlal, Rajendran Ravishankaran, Radhika Nagamangalam Shridharan, Ansel Vishal Lawrence, Anjali Anoop Karande and Kaliraj P. Evaluation of Brugia malayi sheath protein (Shp-1) as a diagnostic antigen for human lymphatic filariasis. Diagnostic Microbiology and Infectious Disease. 2014, 78(3): 249-254 (Impact Factor: 2.568)
• Aparnaa Ramanathan and Kaliraj Perumal. Immunomodulation of ALT-2 and TLR may collude in antigen specific T cell hyporesponsiveness: proposed mechanism for elevated IL-10 levels in Balb/C mice. Acta Parasitologica. 2014, 59(1): 25-30 (Impact Factor: 1.144)
• Chakkaravarthy Arunkumar, Chakkaravarthy Arunkumar, Pandurangan Pandiaraja, P. R. Prince, Perumal Kaliraj. Immunological characterization of recombinant Wuchereria bancrofti cuticular collagen (COL-4) as putative vaccine candidate for human lymphatic filariasis. Asian Pacific Journal of Tropical Medicine. 2014, 412-420 (Impact Factor: 0.672)
• Moorthy Sakthidevia, Prince Rajaiah Prabhua, Swati Chowdharya,Sugeerappa Laxmanappa Hotib, Perumal Kaliraj. Functional analysis of genetic polymorphism in Wuchereria bancroftiglutathione S-transferase antioxidant gene: Impact on proteinstructure and enzyme catalysis. Molecular and Biochemical Parasitology. 2013, 192: 10-20 (Impact Factor: 2.243)
• Anugraha G, Madhumathi, Prince R P, Jeya Prita, Kaliraj P. Molecular Characterisation of VAH-TRX fusion protein for immunoporphylactic potential in lymphatic filariasis, Acta Parasitologica. 2013, 58(4):468-477 (Impact factor: 0.965)
• Natarajan Mahalakshmi, Ramanathan Aparnaa, Lawrance Ansel Vishal and Perumal Kaliraj. Molecular characterization and evaluation of Onchocerca volvulus-secreted larval acidic protein 1 (SLAP1) as a putative vaccine candidate on endemic population of lymphatic filariasis, Parasitology Research. 2013, 112(9): 3203-3211 (Impact Factor: 2.852)
• P.R.Prince, J. Madhumathi, G. Anugraha, P.J. Jeyaprita, M.V.R. Reddy and P. Kaliraj. Tandem antioxidant enzymes confer synergistic protective responses in experimental filariasis. Journal of Helminthology. 2013, 1-9 (Impact Factor: 1.303)
• Sam Sharmila, Immanuel Christiana, Pote Kiran, Maryada V R Reddy, Krishnan Sankaran, Kaliraj P. Bacterial lipid modification enhances immunoprophylaxis of filarial Abundant Larval Transcript-2 protein in Mastomys model. Parasite Immunology. 2013, 1-13 (Impact Factor: 1.849)
• Rohit Sharma, S. L. Hoti, R. L. Meena, V. Vasuki, T. Sankari, Kaliraj P. Molecular and functional characterization of macrophage migration inhibitory factor (MIF) homolog of human from lymphatic filarial parasite Wuchereria bancrofti. Parasitology Research. 2012, 111:2035–2047 (Impact Factor: 2.852)
• Setty Balakrishnan Anand, Vasudevan Rajagopal and Perumal Kaliraj. Brugia malayi thioredoxin peroxidase as a potential vaccine candidate antigen for lymphatic filariasis. Applied Biochemistry and Biotechnology. 2012, 167:1351-1364 (Impact Factor: 1.893)
• Sharmila S, Christiana I, Kiran P, Reddy M V R, Kaliraj P. The adjuvant-free immunoprotection of recombinant filarial protein Abundant Larval Transcript-2 (ALT-2) in Mastomys coucha and the immunoprophylactic importance of its putative signal sequence, Experimental Parasitology. 2011, 129:247–253 (Impact Factor: 2.122)
• Anand S. B, Kodumudi, K.N, Reddy M.V, and Kaliraj P. A combination of two Brugia malayi filarial 2 vaccine candidate antigens (BmALT-2 and BmVAH) enhances immune responses 4 and protection in jirds. Journal of Helminthology. 2011. 85:442-452 (Impact Factor: 1.38)
• Vivek Pandey, Jayaprakasam Madhumathi, Anjali A. Karande, Kaliraj P. Antigen detection assay with parasite specific monoclonal antibodies for diagnosis of lymphatic filariasis, Clinica Chimica Acta. 2011. 412:1867–1873 (Impact Factor: 2.535)
• Madhumathi J, Anugraha G, Prince P.R and Kaliraj P. Proliferative responses of Brugia malayi TPX-1 and its epitopic peptide29–43 in an endemic population of human lymphatic filariasis, Microbes and Infection. 2011, 13:602-606 (Impact Factor:3.101)
• Janardhan S, Pandiaraja P, Vivek Pandey, Anjali Karande and Kaliraj P. Development & characterization of monoclonal antibodies against WbSXP-1 for the detection of circulating filarial antigens. J. Helminth. 2010, 85:1-6 (Impact Factor: 1.544)
• Pandiaraja P, Arunkumar C, Hoti S.L, Rao D.N, Kaliraj P., Evaluation of synthetic peptides of WbSXP-1 for the diagnosis of human lymphatic filariasis. Diagnostic Microbiology and Infectious Disease. 2010, 68:410-415 (Impact Factor: 2.426)
• Madhumathi J, Prince PR, Anugraha G, Kiran P, Rao DN, Reddy MV, Kaliraj P. Identification and characterization of nematode specific protective epitopes of Brugia malayi TRX towards development of synthetic vaccine construct for lymphatic filariasis. Vaccine. 2010, 28:5038–5048 (Impact Factor: 3.572)
• Madhumathi J, Prince P, Rao D N, Kaliraj P. Dominant T cell epitopes of filarial Bm ALT-2 and their cytokine profile in Balb/c mice. Parasite Immunology. 2010, 32:760-763 (Impact Factor: 2.357)
• Madhumathi J, Prince PR, Gayatri SC, Aparnaa R. and Kaliraj P. Identification of a highly immunoreactive epitope of B.malayi TPx recognized by the endemic sera. Journal of Parasitology. 2010, (Impact Factor: 1.208)
• Madhumathi J, Pradiba D, Prince PR, Rao DN and Kaliraj P. Crucial epitopes of Wuchereria bancrofti abundant larval transcript recognized in natural infection. Eur. J. Clin. Microbiol. Infect. Dis. 2010, 29:1481-1486 (Impact Factor: 2.631)
• Pandiaraja P, Murugan V, Hoti SL and Kaliraj P. Molecular characterization of a truncated antigen (Wb14) of SXP-1 of Wuchereria bancrofti from four endemic regions in India. Exp. Parasitol. 2010, 125:236-243 (Impact Factor: 1.869)
• Sakthidevi M, Murugan V, Hoti SL and Kaliraj P. Lymphatic Filarial species differentiation using evolutionarily modified tandem repeats: Generation of new genetic markers. Inf. Gen. & Evol.  2010, 10:591-594 (Impact Factor: 3.086)
• Uma V, Vivek P, Prince R. Prabhu, Gajalakshmi D, MVR Reddy and Kaliraj P. Evaluation of immunoprophylactic efficacy of B. malayitransglutaminase (BmTGA) in single and multiple antigen vaccination with bmalt-2 and bmtpx for human Lymphatic Filariasis. Am. J Trop. Med. & Hyg. 2009, 80(2): 319-324 (Impact Factor: 2.795)
• Anand S. B, Murugan. V; Prince R P, Anandharaman V; Reddy M V R; Kaliraj P. Comparison of Immunogenicity, protective efficacy of Single and Cocktail DNA vaccine of B. malayi abundant larval transcript (ALT-2) and thioredoxin (TPX) in Mice. Act. Trop. 2008. 107(2):106-112 (Impact Factor: 1.707).
• S. Janardhan, P. Pandiaraja, S. Thiruganam, M.N. Balamurali, Kennedy Fernando, S. Meenakshisundaram and P. Kaliraj. Optimization of Production, Purification and Applications of a Diagnostically Important Recombinant Protein WbSXP-1 Expressed inSalt Inducible E.coli. J of Ind. Microbiol & Biotech. 2007, 34: 675-683 (Impact Factor: 2.062)
• Thirugnanam, S, Pandiaraja, P, Ramaswamy, K, Murugan, V, Gnanasekar, M, Nandakumar, K, Rami Reddy, MV, and Kaliraj, P. B. malayi: Comparison of protective immune responses induced Bm-alt-2 DNA, recombinant Bm-ALT-2 protein and prime boost vaccine Regimens in a jird model, Exp. Parasitol 2007, 116(4): 483-491 (Impact Factor: 1.597)
• Uma V, Geetha M, V Murugan and Kaliraj P. Isolation and Characterization of recombinant Brugian parasitic Transglutaminase. Ind. J. of Biotech. 2006, Vol 5 (suppl): 317-326 (Impact Factor: 0.510)
• Vijay Bhaskar, Lakshmi Kanthan, Srikanth T, Suba S, Mody H, Desai P, Kaliraj P, Development and evaluation of a rapid flow through immunofiltration test using recombinant filarial antigen for diagnosis of Brugian and Bancroftian filariasis. Microbiol. Immunol. 2004, 48(7): 519-525 (Impact Factor: 1.44)
• Ravi V, Kubofcik J, Bandopadhyaya S, Geetha M, Narayanan RB, Nutman TB, Kaliraj P.W. bancrofti: cloning and characterization of heat shock protein 70 from the filarial parasite. Exp. Parasitol.2004, 106(1-2):1-10 (Impact Factor: 1.347)
• Eswaran Devarajan, Pankaj Kumar Mishra, Shiva Thirugnanam, Kapil Mehta, Ramaswamy Chandrasekar and Kaliraj Perumal. Molecular characterization of a Brugia malayi transglutaminase. Parasitology research. 2004, 93:145-150 (Impact Factor: 1.06)
• Lalitha P, Eswaran D, Gnanasekar M, Rao KVN, Narayanan RB, Scott AL, Nutman TB and Kaliraj P. Development of antigen detection ELISA for diagnosis of brugian and bancroftian filariasis using antibodies to recombinant filarial antigens BmSXP-1 and Wb-SXP-1, Microbiol & Immunol. 2002, 46(5):327-332 (Impact Factor: 1.17)
• Gnanasekar M, Rao, KVN, Chen L, Narayanan, RB, Geetha M, Scott, AL, Ramaswamy K and Kaliraj P. Molecular characterization of a calcium binding translationally controlled tumor protein homologue from the filarial parasites., Mol. & Biochem. Parasitol. 2002, 121:107-118 (Impact Factor: 2.882)
• Bhuvanesh S, Arunkumar C, Kaliraj P, Ramalingam S., Production and single-step purification of Brugiamalayi abundant larval transcript (ALT-2) using hydrophobic interaction chromatography. J. Ind. Microbiol. Biotechnol. 2010, 37:1053-1059 (Impact Factor: 2.416)
• Janardhan S, Srinivasa Babu K, Kaliraj P, Meenakshisundaram S. Optimization of Media for Expression and Economic Production of Recombinant Proteins of Therapeutic and Diagnostic Interest in a Novel Osmotically Inducible E.coli GJ1158. Res. J Biotech. (2007) 2(1):49-55 (Impact Factor: 1.07)
• Setty Balakrishnan Anand, MunirathinamGnanasekar, Mani Thangadurai, Prince R. P, Kaliraj P and Ramaswamy K. Immune response studies with Wuchereria bancrofti vespid allergen homologue (WbVAH) in human lymphatic filariasis, Parasitol. Res. 2007. 10.1007/s00436-007-0571-2 (Impact Factor: 1.437)
• Sasisekhar B, Aparnaa M, Augustin DJ, Kaliraj P, Kar SK, Nutman TB and Narayanan RB. Diminished Monocyte function in microfilaremic patients with lymphatic filariasis and its relationship to altered lymphoproliferative responses. Infect. Imm. 2005.Vol. 73(6): 3385 –3393 (Impact Factor: 4.004)
• Gnanasekar M, Rao KVN, Mishra PK, Kaliraj P et al. Novel pahge display-based subtractive screening to identify vaccine candidates of Brugia malayi. Infection and immunity. 2004, 72(8): 4707-4715 (Impact Factor: 4.004)
• Nookala S, Srinivasan S, Kaliraj P, Narayanan RB, Nutman TB. Impairment of tetanus-specific cellular and humoral responses following tetanus vaccination in filariasis. Infect. and Immun. 2004, 72 (5):2598-2604 (Impact Factor: 4.004)
• Lammie PJ, Gary W, Rahmah N, Kaliraj P, et al “Recombinant antigen-based antibody assays for the diagnosis and surveillance of lymphatic filariasis – a multicenter trial” Fil. J 2004.3(9): 1-5 (Impact Factor: 1.371)
• S Ramachandran, MP Kumar, RMV Rami, HB Chinnaiah, T Nutman, P Kaliraj and J McCarthy. The larval specific lymphatic filarial ALT-2: induction of protection using protein or DNA vaccination. Microbiol. Immunol. 2004, 48 (12): 945-955 (Impact Factor: 1.44)
• Fred Engelbrecht, Tobias Oettl, Usrula Herter, Claudia Link, Diana Philipp, Henry Edeghere, Kaliraj P, Felicia Enwezor, Analysis of Wuchereriabancrofti infections in a Village community in northern Nigeria: Increased prevalence in individuals infected with Onchocerca volvulus”, Parasitol. Int. 2003, 52: 13-20 (Impact Factor: 1.205)
• Kannan Kunchithapautham, B. Padmavathi, R.B. Narayanan, P. Kaliraj and Alan L. Scott. Thioredoxin from Brugia malayi: Defining a 16-Kilodalton class of thioredoxins from nematodes. Infection and immunity. 2003, 71(7): 4119-4126 (Impact Factor: 4.004)
• Rao KVN, Eswaran M, Ravi V, P Kaliraj et al. The Wuchereria bancrofti orthologue of Brugia malayi SXP1 and the diagnosis of bancroftian filariasis. Mol. Biochem. Parasitol. 2000, 107:71-80 (Impact Factor: 2.397)
• Steve Williams, Mark Blaxter, P Kaliraj et al. Deep within the filarial genome: Progress of filarial genome project. Parasitology Today. 1999, 15(6):219-224 (Impact Factor: 4.94)
• Uma R, Eswaran D, Narayan RB, Jayaraman K and Kaliraj P. Proinflammatory cytokines secreted by monocytes of filarial patients. Microbiol. Immunol. 1999, 43(3): 279-283 (Impact Factor: 1.17)
• Regunathan J, Jayaraman K and Kaliraj P. Cellular immune response studies in bancroftian filariasis. Journal of Helminthology. 1997, 71(3):265-267 (Impact Factor: 0.491)
• P Lathila, M Ravichandran, S. Suba, P. Kaliraj, R.B. Narayanan and Kunthala Jayaraman. Quantitative assessment of circulating antigens in human lymphatic filariasis: a field evaluation of monoclonal antibody-based ELISA using blood collected on filter strips. Tropical medicine and international health. 1998, 3(1): 41-45 (Impact Factor: 0.997)
• JG Theodore, P Kaliraj, S Jayachandran and K Jayaraman. Cloning, over-expression and evaluation of a recombinant fusion protein of Wuchereria bancrofti towards its application as a diadnostic agent for bancroftian filariasis. Parasitology. 1993, 106: 413-420 (Impact Factor: 2.01)
• Kannan K, Latitha P, Rao KV, Narayanan RB and Kaliraj P. Optimisation of immunoaffinity purification of Wuchereria bancrofti specific antibodies from human sera. Indian J Exp Biol. 1997, 35(10):1076-1079 (Impact Factor: 0.93)
• Usha Jain, Patel MT, Desai PK and Kaliraj P. Development of simple and stable ELISA for detection of copro antigen in intestinal amoebiasis. Indian J Exp Biol. 1990, 28: 671-675 (Impact Factor: 0.93)
• J.G. Theodore and P. Kaliraj. Wuchereria bancrofti recombinant antigen-derived poly- and monoclonal antibodies for the detection of circulating antigen(s) in the sera of lymphatic filarial patients. Journal of Helminthology. 1996, 70:69-74 (Impact Factor: 0.491)
• J.G. Theodore and P. Kaliraj. Isolation, purification and characterization of surface antigens of the bovine filarial parasite Setaria digitata for the immunodiagnosis of bancroftian filariasis. Journal of Helminthology. 1990, 64(2):105-114 (Impact Factor: 0.491)
• P Kaliraj, SN Ghirnikar and BC Harinath. Enzyme linked immunosorbent assay (ELISA) for bancroftian filariasis. Trans Roy. Soc. Trop. Med. Hyg. 1981, 75:119-120 (Impact Factor: 1.931)
• P Kaliraj, Indira Kharat, SN Ghirnikar and BC Harinath. The utility of human filarial serum in the detection of circulating antigen. Journal of Helminthology. 1981, 55:133-139 (Impact Factor: 0.491)
• P Kaliraj, SN Ghirhikar and BC Harinath. Immunodiagnosis of bancroftian filariasis: comparative efficiency of the indirect hemagglutination test, indirect fluorescent antibody test and enzyme-linked immunosorbent assay done with Wuchereria bancrofti microfilarial antigens. Am. J. Trop. Med. Hyg. 1981, 30(5): 982-987 (Impact Factor: 1.931)
• Usha Jain, PK Desai, MT Patel, DK Joshi and P Kaliraj. Purification and characterization of E.histolytica antigen for diagnosis of amoebiasis. Indian J Exp Biol. 1990, 28:1118-1123 (Impact Factor: 0.93)
• Usha Jain, Parul Desai, Kaliraj P et al. Evaluation of Tri-iodide resin for bacterial purification of drinking water. J Indian water works association. 1986, 18:301-307 (Impact Factor: 0.528)
• Kaliraj P, Madhu T Patel, Gaurang Desai, Rekha Megha and Pradeep K Desai. Utility of human anti-hepatitis B surface antigen serum in purification and detection of hepatitis B surface antigen. Indian J Exp Biol. 1983, 21: 487-493 (Impact Factor: 0.93)
• Malathi S and Kaliraj P. A study on the acetylcholinesterase activity at the neuromuscular junctions in tibialis anterior and soleus muscles of the dog. Current science. 1981. 50 (10): 443-447 (Impact Factor: 0.834)
• Kaliraj P, Ghirnikar SN and Harinath BC. Indirect fluorescent antibody technique using sonicated Wuchereria bamcrofti microfilaria for immunodiagnosis of bancroftian filariasis. Indian J Exp Biol. 1979, 17: 332-335 (Impact Factor: 0.93)
• Kaliraj P, Rao KN, Harinath BC and Ghirnikar SN. Immunization studies in rabbits with human-filarial parasite. Indian J Exp Biol. 1978, 16: 994-995 (Impact Factor: 0.93)

Awards

• Sir J.C. Bose Memorial award for his contribution in the field of Science
• Honorary Colonel award conferred by the Ministry of Defence, New Delhi.
• Senior Scientist Oration award by Indian Immunology Society, 2013
• Life time Achievement award by Biotechnology Research Society of India, 2013
• Dr. B.N.Singh Memorial Oration award by Indian Parasitology Society, 2011
• Dr.B.P.Pandey Memorial Oration award (Indian Parasitology society) 2010
• BRSI Industrial medal of Biotechnology Research Society of India, 2003
• Prof. B.K.Aikat Oration award by Indian Council for Medical Research, 2002
• Fellow, National Academy of Biological Sciences, 2008
• Fellow, Biotechnology Research Society of India, 2009

Contribution as Interim Vice Chancellor (Officiating)

• Owing to my long association of holding key positions at the University and I could achieve the following administrative acumen in a short-time of 10 months
• Smooth merger of AUTs and establishment of effective administration including the appointment of Regional Directors for smooth functioning
• Solutions for long-pending issues like hostel facilities and academic infrastructure in constituent colleges
• Smooth conduct of B.E./B.Tech and M.E./M.Tech. single-window admissions and orientation programme for the new set-up in all University colleges
• As vision 2023 Coordinator worked with the Government to initiate programmes worth Rs. 3,950 Crores
• Satellite based faculty development programmes to augment teaching capabilities in constituent and affiliated colleges.
• Mentorship programme for the institutional development in constituent and university colleges
• Strengthening of programmes like Centre for Technology development and Transfer to promote translational research
• Submission of LoI and necessary documents to get the University accredited by NAAC for global competitiveness
• Two-tier scheme to enhance the standards of needy affiliated colleges and employability of their students to bring uniform quality engineering education across the State
• Introduced academic audit to monitor teaching, learning and evaluation process
• Initiative to bring DTH (Direct To Home) into teaching and training students and faculty at home beyond college timings
• Strengthened CFD for improving quality of teachers
• First syndicate meeting after merger for resolving pressing issues
• First convocation and graduation day of the university after merger

Contribution as DEAN of A.C. Tech Campus

• Up-gradation of academic and research programme of the 5 Technical departments, namely Chemical Engineering, Textile Technology, Leather Technology Ceramic Technology and Centre for Biotechnology and secured NBA accreditation with high credits
• Started PG courses in the emerging frontier areas such as nanotechnology, Food Technology and Apparel Technology were introduced
• Learning experience of the students and research capabilities of the staff were enhanced with additional modernized class rooms, laboratories, workshops, campus networking, sophisticated instrumentation and infrastructure for research
• Special coaching in English for Tamil medium students to cope with change of medium
• With emphasis on increased placement of students in core industries we have been able to reverse the blind IT trend much to the benefit of the students and technological advancement of our country
• Contributed proactively to the policies and guidelines of services and recruitment of faculties
• Hostels have been modernized with latest kitchen facilities
• Instrumental in rationalizing and simplifying purchase procedures
• Implemented a highly successful training programme for faculty and students both at national and international levels to build futuristic competence in emerging areas
• As a coordinator of technology Quality Improvement Programme (TEQIP) funded by World Bank, I have brought about all round development of A.C. Tech Campus, from beautification to Computer Net-working to benefit both faculty and students
• Several Service to Society programmes were conducted with the conviction of taking useful engineering and technology knowledge to common man
• First MHRD Centre of Excellence for Biomedical Application proposed with the budget of Rs. 10 Crores was selected for funding

Contribution as the Director-Centre for Biotechnology

• DBT grant for M.Tech. teaching programme: Rs. 75 Lakhs in the 9th plan and 1 crore in the 10th plan
• DBT-sponsored national BTIS programme: Rs. 50 Lakhs in the 9th plan and 2 crores for 10th plan
• Under FIST programme in a national competitive evaluation DST rated the Centre as a unique teaching facility in Biotechnology and awarded Rs. 50 Lakhs for the upgradation of its practical laboratory for HRD programme
• Projected advancements in Infectious diseases research as a thrust area and got the induction of Departmental Special Assistance programme of UGC to the tune of Rs. 1 crore from Phase I and II. This will lead to getting financial assistance for next 20 years till establishment of advanced centre
• Impressed NAAC committee with the achievements of the department, including international publications and funding, and helped to get the five star status for Anna University
• Student exchange programmes have been implemented with foreign universities like UTC, France and University of Leicester, UK., University of Glasgow, UK, Aim Shan University, Egypt, University of Heidelburg, Germany, University of Rockford and NIH, USA
• Negotiated successfully for student placement in other universities like National University of Singapore, KRDL Singapore etc
• The Centre was developed into the best model in Biotech education and research in University set-up, as revealed by the interest shown by DBT and a number of institutions in the nation to adopt our curriculum and training
• In fact, the department was recognized by major funding agencies like DST under FIST programme and UGC under DSA programme. These special recognitions and funding were used to vastly improve infrastructure and advance in frontier areas of research in infectious diseases especially filariasis and diarrhoeal diseases
• In a major capacity expansion owing to the public demand and the Government’s policy the annual intake for UG programme increased from 20 to 60 and five other such Centres were opened in constituent Government Engineering Colleges of Tamil Nadu; Intake of M.Tech. Went up from to 12 to 40
• Research was diversified in to new and emerging areas of Biotechnology and more Ph.D. students were enrolled, their strength increasing from 22 to 40
• Having had the benefit of both industrial experience and academic insight, intensified product-oriented research to develop products and process. This led to 2 products by self and several products, prototypes and process from colleagues
• For the first time in India a Technology Business Incubator for Biotechnology was started at the Centre with a seed grant from DST-UNDP in 2003. Within the past 5 years many small entrepreneurs have made use of this facility and it has now become a self-supporting entity
• Industrial consortium which plays crucial role in the running of the department, was increased several fold and the funds generated was used to create faculty positions, enhanced infrastructure

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