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Department of Biotechnology Anna University

Dr. Pennathur Gautam

Professor, Centre for Biotechnology

Anna University, Chennai 600025



Degree Year University Major Subject Studied
Ph D 1989 Indian Institute of Science, Bangalore, India Inorganic & Physical Chemistry , Studies on Porphyrins & Their Metalloderivatives , Advisor: Prof. V. Krishnan
M. Sc. 1981 Vivekananda College, University of Madras Chemistry
B. Sc. 1979 Vivekananda College , University of Madras Major: Chemistry, Minor: Physics & Chemistry

Positions Held– Academic

2004– till date Professor, Chemical Biology & Computational Biology, Anna University
1996–2004 Assistant Professor, Chemical Biology & Computational Biology, Anna University
1993–96 Visiting Faculty, Bioorganic Chemistry, Anna University, Chennai
1992–93 Post Doctoral Fellow, Time–Resolved Spectroscopy of Biological Molecules, Centre for Fast Kinetics Research University of Texas Austin
1989–92 Research Associate, Time–Resolved EPR Spectroscopy of Biradicals. Advisor: G.L. Closs, Department of Chemistry , University of Chicago
03.07.1981 to 04.08.1998 Research Associate, Time–Resolved EPR Spectroscopy of Biradicals. Advisor: G.L. Closs, Department of Chemistry , University of Chicago

Positions Held–Administrative

2016 – Present Director AU - KBC Research Centre, Anna University
2013 – 2016 Head, Department of Biotechnology, Anna University
2008 - 2013 Chairperson, Faculty of Technology, Anna University

Present Position of Former Group Members

Name Area of Work Position Affliation
Dr. B.S.Lakshmi Bioorganic Chemistry Associate Professor Centre for Food Technology, Anna University
Dr. V.Anuradha Proteomics Post–Doctoral Fellow University of Michigan, U.S.A
Dr. Ramalingam. S Bioprocess Technology Associate Professor Centre for Biotechnology Anna University
Dr. Sharmila Anishetty Computational Biology Assistant Professor Centre for Biotechnology, Anna University
Dr. Jayant James Molecular Simulations Post–Doctoral Fellow Fox Chase Institute, U.S.A
Dr. Richard . W Metal Resistant Microorganisms Assistant Professor SRM University, Chennai
Dr. Kavitha R Enzyme Technology Scientist E. Merck, U.S.A
Dr. S. Karthikeyan Genomics & Proteomics Head Bioinformatics Positive Biosciences , Mumbai
Dr. C. S. Latha Industrial Microorganisms Research Associate, DBT Anna University Chennai
Dr. K. S. Vinod Pharmaceutical Chemistry Reseach Scientist Chemicals
Dr. R. Kaushik Food Technology Senior Consultant Giract Consultantcies
Dr. A. Nandhini Enzyme Technology Analyst Frost & Sullivan.
Dr. M. Saminathan Enzyme Technology Post–Doc University of Illinois , USA
Dr. Vinatha Krishna Molecular Simulations DBT , Post-Doc Anna University Chennai
Dr. V. Sujatha Science Communication Analyst Frost & Sullivan
Dr. J. Narayanan Nanobiology Senior Scientist Sankar Netralaya
Dr. K. S. Senthil Protein Purification Post–doc University of Florida, USA
Dr. K. Thirumalaimuthukumaresan Protein Purification Research Associate Evolvo Biosciences
Dr. T.Kothai Molecular Simulations Member–Research Centre for Biotechnology, Anna University
Dr. G. Nandhini Devi Environmental Biotechnology Associate Professor Centre for Food Technology , Anna University
Dr. N. Velu Enzyme Technology Administrative Staf Department of Mechanical Engineering, Anna University
Dr. Abhilash Computational Biology Post–Doc I.I.Sc
Dr.K. Divakar Enzyme Technology DST - INSPIRE Faculty NIT Warangal
Dr. Ashwin. K Biofilms Assistant Professor VNIT, Nagpur

Graduate Students ( Ph.D )

Name Degree Year Area of Work Thesis Title
Dr.B.S.Lakshmi Ph.D 2000 Lipases and Monooxygenases Studies on Candida rugosa Lipase and its Stereospecificity towards Resolution of Racemic Ibuprofen
Dr.V.Anuradha Ph.D 2004 Metal Resistant Microorganisms Studies on Thiobacillus ferrooxidans and Serratia Marsescens on their Metal Affinity and Pigment Secretion
Dr.Ramalingam. S Ph.D 2005 Bioprocess Technology Bioprocess Strategies for Enhanced Production of Recombinant Streptokinase in E.coli
Dr.Sharmila Anishetty Ph.D 2005 Computational Biology & Molecular Modeling Studies on Protein structure: Tripeptide Analysis and its Application
Dr.Jayant James Ph.D 2005 Molecular Simulations Studies on Molecular Dynamics Simulation of Lipases
Dr.Richard .W Ph.D 2005 Metal resistant Microorganisms Studies on Microbial Leaching of Lignite using Bacillus cereus & Acidothiobacillus Ferrooxidans
Dr. Kavitha R Ph.D 2006 Secretion of Lipases Studies on Lipase Production by Candida rugosa using Oil Seeds as Substrates
Dr. C. S. Latha Ph.D 2008 Secretion of Lipases & Molecular Dynamics Simulations Studies on Pseudomonas aeruginosa Lipase : Secretion & Molecular Dynamics Simulations
Dr. S. Karthikeyan Ph.D 2008 Genomics Studies on Landscape Elements in Genomic DNA
Dr. K. S. Vinod Ph.D 2008 Pharmaceutical Chemistry Studies on Embedded Tamarind Seed Polysacharride Matrices
Dr. R. Kaushik Ph.D 2009 Food Technology Studies on Isolaton of Steveoside
Dr. A. Nandhini Ph.D 2009 Industrial Microbiology Studies on Lipase from Serratia Marcasens
Dr. M. Saminathan Ph.D 2009 Industrial Enzymes Studies on Esterase from Lysinbacillus sphaericus
Dr. Vinatha Krishna Ph.D 2009 Molecular Simulations Studies om Molecular Dynamics of N-Acetytransferase
Dr. J. Narayanan Ph.D 2010 Nanobiotechnology Studies on Rhamnolipid from Pseudomonas aeruginosa and its Applications
Dr. V. Sujatha Ph.D 2010 Bioanalysis Studies on Metal Tolerant Bacteria & Applications of Porphyrin Derivatives
Dr. K. Senthil Kumar Ph.D 2011 Molecular Biology Studies on Mercury Transporter (merT)and Mercury Reductase (merA) Proteins
Dr. K. T. Kumaresan Ph.D 2011 Industrial Enzymes Studies on Lipases from Aeromonas veronii PG01
Dr.Sharmila Anishetty Ph.D 2005 Computational Biology & Molecular Modeling Studies on Protein structure: Tripeptide Analysis and its Application
Dr. Deepa Priya Ph.D 2012 Industrial Enzymes Studies on protease from Bacillus megatarium
Dr. T. Kothai Ph.D 2012 Molecular Simulations Studies on understanding domain movements and interaction of Pseudomonas aeruginosa lipase, Rhizomucor miehei lipase and Candida rugosa lipase with a lipid molecule: A Molecular Dynamics Approach
Dr. G. Nandhini Devi Ph.D 2013 Industrial Enzymes Studies on Production , Purification and Characterization of Lipase from Acenitobacter sp. AU07
Dr. N. Velu Ph.D 2013 Industrial Enzymes Studies on Isolation , Production , Purification and Characterization of Lipase from Aeromonas caviae AU04
Dr. Abhilash. M Ph.D 2014 Computational Biology Studies on the Application of Machine Learning Algorithms in Computational Biology
Dr. K. Divakar Ph.D 2014 Bioprocess Studies on esterase from Lysinibacillus fusiformis and substrate selectivity analysis of lipases/esterases
Dr. Divya Rao Ph.D 2014 Nanobiology Studies on synthesis and characterization of gold and semiconductor nanoparticles using Chlamydomonas reinhardtii
Dr. M. Priyadharshini Ph.D 2014 Computational Biology Studies on periplasmic chaperone lolA and outer membrane protein lolB in E.coli an analysis of lipoprotein interactions leading to identification of inhibitors: A molecular dynamics and in-silico study
Dr. G. PanneerselvamM Ph.D 2015 Microbiology Studies on Isolation, Production and Purification of Lipase from Acinetobacter radioresistens AU06

Post-Graduate Students ( M.S )

Name Degree Year Area of Work Thesis Title
T. Kothai M.S 2006 Molecular Simulations Analysis of Lipase Sequences in Terms of Tripeptides
Ashwin K M.S 2008 Biochemical Engineering A Study of the Extractive Fementation of Esterase from Bacillus sp. Using Aqueous Two Phase Systems
K. Divakar M.S 2010 Industrial Microbiology Studies on Extracellular Protease Isolated from Aeromonas veronii
Abhinaya Sindhu M.S 2011 Biofilms Studies on EPS Characterstics of Pseudomonas aeruginosa Biofilms Grown in different Metal fatty Acid Medium
N. Vijina M.S 2012 Nanobiology Studies on Phosphorylated Rhamnolipids

Grant and Contract Support: Ongoing Projects

Agency Title Year Grant
Department of Biotechnology Foldscope 2018-19 Rs. 8,00,000/-

Grant and Contract Support: Completed Projects

Agency Title Year Grant
Department of Biotechnology Systems Approach to understand Quorum sensing in Serratia marsescens PI : P. Gautam , Co–PI Sharmila Anishetty 2013–16 Rs. 88,00,000/-
University Grants Commission Computer Simulation of DNA 1998–01 Rs. 4.00,000/-
Department of Science Biomolecular Dynamics: Simulation of Lipases in Aqueous nad Non-aqueous solvents 1999-02 Rs. 13,00,000/-
Department of Biotechnology α/β Fold Prediction of Lipases 2001-04 Rs. 12,00,000/-
Department of Science & Technology Biosurfactant Production PI: P. Gautam, Co–PI: V. Murugan 2005-09 Rs. 25,48,000/-
Department of Science & Technology Nanotechnology PI‘: P. Gautam, Co–PI’s: Sharmila Anishetty, R. B. Narayanan, B.S. Lakshmi 2006-09 Rs. 1,00,07,000/-
Department of Biotechnology Detection of Rice Tungro Virus PI: P. Gautam, Co–PI: P.V. Ramakrishna 2007–10 Rs. 55,00,000/-
Department of Science & Technology Biofilm Formation PI: P. Gautam, Co–PI: B. S. Lakshmi 2009–12 Rs. 39,96,000/-
Department of Biotechnology Hydrogen Production From Algae PI: P. Gautam, Co–PI: B. S. Lakshmi 2010-12 Rs. 48,04,000/-
Department of Biotechnology DBT Program Support for Macromolecular Engineering & Design Anna University & Madurai Kamaraj University Coordinator : P. Gautam Co–Leader : S. Krishnaswamy,Co–PI’s: R. Usha,Sharmila Anishetty, B. S. Lakshmi,G. Nandhini Devi, S.Ramalingam 2008–14 Rs. 5,03,00,000/-

Patents Filed

• Process For Preparing rhamnolipid capped metal nanoparticles. Pennathur Gautam, Narayanan Janakiraman,:Centre fo Biotechnology, Anna University, Chennai - 600025, Tamilnadu India, Patent Application Publication, Application No.2143/CHE/2008 A India Date of filing of Application :02/09/2008 Publication Date : 21/11/2008. The Patent Office Journal

• A Method to detect hydrolases and in-gel staining of proteins using tetra (4-sulphonato phenyl) porphyrin. P.Gautam , V.Sujatha ,K.S.Vinod Kumar D.Leelavathi. Application No.3161/CHE/2008 A. Date of filing of Application :16/12/2008 (43) Publication Date : 20/02/2009 The Patent Office Journal

• A Method for microbial production of extracellular lipase using vegetable oilseed substrates. Pennathur Gautam, Cherukuvada Subbalakshmi Latha Application No.375/CHE/2009 A.Date of filing of Application :20/02/2009 Publication Date : 06/03/2009. The Patent Office Journal

• A Process for production of water-based nanofluid using single walled carbon nanotubes. P. Gautam, K.A.Padmanabhan,T.Mohan Das,R. Jayavel,A.Pandurangan, T.Somanathan, N.Rajaram, V. Ganpath Kumar, S. Nagaraja. Application No.2831/CHE/2008 Date of filing of Application :18/11/2008 Publication Date : 30/01/2009. The Patent Office Journal.

• A Method for producing metal oxide nanoparticles using tamarind seed polysaccharide. P. Gautam, B.S. Lakshmi, K.S.Vinod Kumar, V. Sujatha, Appl. No. 832/CHE/2009 A. Date of filing of Application: 09/04/09 Publication Date : 12/06/2009. The Patent Office Journal.

• A Method for live cell imaging of bacterial cells using anionic porphyrins and its metallo derivatives. P. Gautam, V. Sujatha, K.S. Vinod Kumar, Srinath Krishnamurthy, Bharat Sridhar. Appl. No. 1082/CHE/2009 A. Date of filing of Application: 11/05/09 Publication Date: 12/06/2009. The Patent Office Journal.

• A Process for Production and Purification of Thermostable Organic Solvent Protease from Aeromonas vernii PG01. P. Gautam, K. Diwakar & J. Deepa Priya Appl. No. 491/CHE/2010 A. Date of filing of Application: 25/02/2010.


Refereed Journal Articles

  • Green synthesis and characterization of cadmium sulphide nanoparticles from Chlamydomonas reinhardtii and their application as photocatalysts. Divya Rao & Gautam Pennathur Materials Research Bulletin http://dx.doi.org/10.1016/j.materresbull.2016.08.049
  • Facile bio–inspired synthesis of Zinc sulphide nanoparticles using Chlamydomonas reinhardti cell free extract: optimization, characterization and optical properties. Divya rao & Pennathur Gautam Green Processing & Synthesis 5, 379, 2016.
  • Characterization of Biofilms Produced by Pseudomonas aeruginosa in Different Metal Fatty Acid Salt Media. P. Abinaya Sindu & Pennathur Gautam Can. J. Microbiol. , doi: 10.1139/cjm-2015-0384
  • Synthesis of Ag(II) 2,3,7,8,12,13,17,18-Octabromo-5,10,15,20-tetraphenylporphyrin and its facile demetallation to 2,3,7,8,12,13,17,18-Octabromo-5,10,15,20-tetraphenylporphyrin. Sasitha Vidyarani, Anuj Pennathur, Pennathur Gautam & Nandhini Devi. Journal of Porphyrins & Pthalocyanines 20, 656, 2016.
  • Purification and Characterization of a Membrane-Unbound Highly Thermostable Metalloprotease from Aeromonas Caviae. Santhalembi Laishram & Gautam Pennathur. Arab. J. Sci. Eng. 41, 2107, 2016.
  • Structure and simulation of a Zundel ion stabilized by 8-hydroxyquinoline-5, 7 disulphonic acid. Hasthi Annapurna Venkatakrishnan, Ramaseshan Venkatakrishnan, Anuj Krishnasundar Pennathur & Gautam Pennathur. J. Mol. Str. 1115, 119, 2016.
  • Synthesis and characterization of ZnO nanoflowers using Chlamydomonas reinhardtii: A Green Approach. Divya Rao & Pennathur Gautam Environmental Progress & Sustainable Energy 35, 1020, 2016
  • A quantitative study on the formation of Pseudomonas aeruginosa biofilm. Ashwin Kannan & Pennathur Gautam Springer Open 4, 369, 2015.
  • A quantitative study on the effect of calcium and magnesium palmitate on the formation of Pseudomonas aeruginosa biofilm. Ashwin Kannan & Pennathur Gautam. Journal of Microbiology, Immunology and Infection 10.1016/j.jmii.2015.06.001.
  • Process optimization for production and purification of lipase from Acinetobacter sp. AU07. R. Gururaj, G. Nandhini Devi & Pennathur Gautam. Brazilian Journal of Microbiology. 47, 647, 2016
  • A Quantitative study on the effect of “ Hot water treatment’ on Pseudomonas aeruginosa Biofilm using Atomic Force Microscopy. G. Panneerselvam, Ashwin Kannan & Pennathur Gautam. Asian Journal of Microbiology Biotechnology & Environmental Science 16, 941, 2014. .
  • Nanoscale investigation on Pseudomonas aeruginosa biofilm formed on porous silicon using Atomic Force Microscopy. Ashwin Kannan , C. S. Latha, Vinatha Krishna, T. Kothai & Pennathur Gautam Scanning 36, 551, 2014 .
  • A Study on Pseudomonas aeruginosa Biofilm Ashwin Kannan, G. Panneerselvam & Pennathur Gautam Asian Journal of Microbiology Biotechnology & Environmental Science 16, 379, 2014
  • A Facile One–Pot Synthesis of Gold Nanoparticles by Chlamydomas Reinhardtii. Divya Rao & Pennathur Gautam Asian Journal of Microbiology Biotechnology & Environmental Science 16, 633, 2014.
  • Statistical analysis of production of protease and esterae by a newly isolated Lysinibacillus fusiformis AU01: purification and application of protease in sub-culturing cell lines. M. Suryia Prabha, J Deepa Arul Priya, K. Divakar, G Panneer Selvam, Pennathur Gautam Ann. in Microbiol. 65, 33, 2015.
  • Isolation, Purification and Characterisation of an Organic Solvent-Tolerant Ca2+ -Dependent Protease from Bacillus megaterium AU02 J Deepa Arul Priya, K. Divakar, M Suryia Prabha, G Panneer Selvam, Pennathur Gautam. Appl. Biochem. Biotechnol. 172, 910 , 2014.
  • A Multi-Substrate Assay for Lipases/Esterases: Assessing acyl chain length selectivity by RP-HPLC. K.Divakar , Pennathur Gautam K. Divakar, Pennathur Gautam. Analytical Biochemistry 448, 38, 2014
  • Understanding the lid movements of LolA in Escherichia coli using molecular dynamics simulation and in silico point mutation Priyadarshini Murahari, Sharmila Anishetty, Gautam Pennathur. Computational Biology and Chemistry 47, 71, 2013.
  • Resonance Energy Transfer between Protein and Rhamnolipid capped ZnS quantum dots: Application in in-gel Staining of Proteins. Narayanan Janakiraman, Abhilash Mohan, Ashwin Kannan, Gautam Pennathur. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 95, 478, 2012
  • In-Gel Staining of Proteins in Native Poly Acryl Amide Gel Electrophoresis Using Meso–Tetrakis(4-sulfonato phenyl) Porphyrin (TPPS) Divakar. K, G. Nandhini Devi and Pennathur Gautam. Methods in Molecular Biology 869, 579, 2012.
  • Lipase from Aeromonas caviae AU04: Isolation, Purification and Protein Aggregation. N. Velu, K. Divakar, G. Nandhinidevi, Pennathur Gautam Biocatalysis and Agricultural Biotechnology 1, 45, 2011 .
  • In-Gel Staining of Proteins in Native Poly Acryl Amide Gel Electrophoresis Using Tetrakis(4-sulfonato phenyl) Porphyrin (TPPS) Divakar. K, Sujatha. V,, Barath Sridhar, Srinath Krishnamurthy, and Pennathur Gautam. Analytical Sciences 27, 101, 2011.
  • Molecular dynamics simulations of human and dog gastric lipases: Insights into domain movements Anitha Selvan, Chandrabhan Seniya, Srinivas Niranj Chandrasekaran, Nithyanand Siddharth, Sharmila Anishetty, Gautam Pennathur FEBS Letters 584, 4599, 2010.
  • Expression and single-Step purification of mercury transporter (merT) from Cupriavidus metallidurans in E.coli. K. Sendhil & Pennathur Gautam. Biotechnology Letters ,32, 1663, 2010.
  • Use of tetra ammonium tetrakis (4-sulphonato) phenyl porphyrin for bacterial cell imaging. , Sujatha V, Bharat Sridhar, Srinath Krishnamurthy, Vinod Kumar K S, Senthil Kumar K & Gautam Pennathur. International Journal of Analytical Chemistry , Volume 2010, Article ID 697528 .
  • Purification and Characterisation of Thermo-Stable Organic Solvent-Tolerant Protease From Aeromonas veronii PG01 , Divakar K, Deepa Arul Priya J, Pennathur Gautam. Journal of Molecular Catalysis B: Enzymatic, 66, 311 , 2010
  • Global Metal-Ion Binding Protein Fingerprint: A Method to Identify Motif-less Metal-Ion Binding Proteins Abhilash Mohan, Sharmila Anishetty & Pennathur Gautam. Journal of Bioinformatics & Computational Biology . 8, 717 , 2010.
  • Synthesis, Stabilisation and Characterisation of Rhamnolipid Capped ZnS Nanoparticles in Aqueous Medium. Narayanan Janakiraman & Pennathur Gautam. IET Nanobiotechnology 4, 2 , 2010
  • Investigation on Domain Movements of N-Acetyltransferases in Nanoscale. Vinatha Krishna, K. S. Vinod Kumar, Sharmila Anishetty & Pennathur Gautam. Journal of Nanoscience & Nanotechnology 9, 5493, 2009
  • Molecular Dynamics Simulations of Lipases. Kaushik Ramakrisnan, Vinatha Krishna, Vinod kumar K.S, Lakshmi, B.S ,Sharmila Anishetty & Gautam Pennathur. International Journal of Intergrative Biology,2,205, 2008
  • Blue native electrophoresis study on lipases. M. Saminathan, K. Thirumalai Muthukumaresan, Srinivas Rengarajan, Nandhini Muthukrishnan & Pennathur Gautam. Analytical Biochemistry , 377, 270. 2008. (Top 25 Hottest Articles in Analytical Biochemistry, April – June 2008, Article No: 13, http://top25.sciencedirect.com/subject/biochemistry-genetics-and-molecularbiology/3/journal/analytical-biochemistry/00032697/archive/18/)
  • Activation of Candida rugosa lipase at alkane–aqueous interfaces: A molecular dynamics study . J . James , B . Lakshmi , A . Seshasayee , P . Gautam. FEBS Letters , 581 , 4377,2007 .
  • Distribution of Tripeptides in MHC Binding Peptides. Sharmila Anishetty & Gautam Pennathur. Protein and Peptide Letters, 14, 552 , 2007.
  • In silico identification of putative metal binding motifs Richard Thilakaraj , Krishnan Raghunathan ,Sharmila Anishetty & Gautam Pennathur. Bioinformatics 23, 267, 2007.
  • Effects of post-induction feed strategies on secretory production of recombinant streptokinase in Escherichia coli Subramanian Ramalingam, Pennathur Gautam, Krishna Jyoti Mukherjee and Guhan11. Jayaraman. Biochemical Engineering Journal, 33, 34 , 2007.
  • Accumulation of Acid Orange 7, Acid Red 18 and Reactive Black 5 by growing Schizophyllum commune S. Renganathan, W. Richard Thilagaraj, Lima Rose Miranda, P. Gautam, M. Velan. Bioresource Technology 97, 2189 , 2006.
  • A Sensitive Assay for Lipase using Tetra Sulfonatophenyl Porphyrin. K.S. Vinod Kumar, Bharathi Ramasubhan, B.S. Lakshmi and Pennathur Gautam. Analytical Biochemistry 356, 294, 2006.
  • Understanding mutations and protein stability through tripeptides. Sharmila Anishetty, Ramesh Anishetty and Gautam Pennathur. FEBS Letters 580, 2071 , 2006
  • Role of Hydrophobic Interactions and Salt–Bridges in β Hairpin Folding. Aswin Sai Narain Seshasayee, Krishnan Raghunathan, Karthikeyan Sivaraman, Gautam Pennathur. J. Mol. Mod. 12, 197, 2006.
  • Potential Drug Targets in Mycobacterium tuberculosis through Metabolic Pathway Analysis. Sharmila Anishetty , Mridula Pulani , Pennathur Gautam. Computational Biology and Chemistry, 29, 368 , 2005., Analytical Biochemistry , 377, 270. 2008. (Top 25 Hottest Articles in Computational Biology & Chemmistry January–March 2006, Article No: 1, http://top25.sciencedirect.com/subject/biochemistry-genetics-and-molecularbiology/3/journal/computational-biology-and-chemistry/14769271/archive/7/)
  • Evidence of a Double-Lid Movement in Pseudomonas aeruginosa Lipase: Insights from Molecular Dynamics Simulations. Subbulakshmi Latha Cherukuvada, Aswin Sai Narain Seshasayee,Krishnan Raghunathan,Sharmila Anishetty, Gautam Pennathur. PLoS Computational Biology 1, e28, 2005.
  • Promoter Addresses: Revelations from Oligonucleotide Profiling Applied to the Escherichia coli genome. Karthikeyan Sivaraman, Aswin Sai Narain Seshasayee, Krishnakumar Swaminathan, Geetha Muthukumaran, Gautam Pennathur. Theoretical Biology and Medical Modelling 2, 20 2005
  • Functionally Specified Protein Signatures for Individual Blue Copper Proteins and for a Combination of Blue and Green and Blue and Purple Copper Proteins. Anuradha V., Sharmila A and Gautam P. BMC Bioinformatics 5, 127 2004.
  • A Novel Medium for the Enhanced Growth and Production of Prodigiosin from Serratia marsescens Isolated from Soil. Anuradha Giri., Nandini Anand Geetha Muthukumaran and Gautam Pennathur BMC Microbiology 4,11 2004. Most Viewed All Time: http://www.biomedcentral.com/bmcmicrobiol/mostviewed/alltime Article 16
  • Insights from Molecular Dynamics Simulation into pH Dependent Enantioselective Hydrolysis of Esters by Candida rugosa Lipase. Jayasunder J James, Baddireddy S Lakshmi, Venkateshamoorthy Raviprasad, Madhuranthagam J Ananth, Pandjassarame Kangueane, Pennathur Gautam. Protein Engineering 16 , 1017 2003. The 50 Most-Frequently-Read Articles in Protein Engineering, Design and Selection during March 2006, http://peds.oxfordjournals.org/reports/mfr9.dtl
  • Tripeptide Analysis of Protein Structures. Sharmila Anishetty; Pennathur Gautam , Ramesh Anishetty. BMC Structural Biology, 2, 9 2002.http://www.biomedcentral.com/bmcstructbiol/mostviewed/alltime : Article No: 8.
  • A Study on the Effect of Hydrophobicity on the Interficial Activation of Candida rugosa Lipase. Lakshmi, B. S; Madhavi, K; Kangueanne, P; Mukut, S; Gautam,P. J. Biochemistry Mol. Biol & Biophyscis, 4, 293 2000
  • Molecular Basis for the Stereospecifiity of Candida rugosa Lipase (CRL) towards Ibuprofen. Lakshmi, B. S; Kangueanne, P; Guo, Y.; Chen, . Z.; Gautam, P. Biocatalysis and Biotransformations , 17, 475 2000.
  • Effect of Vegetable Oils in the Secretion of Lipase from Candida rugosa (DSM 2031). Lakshmi, B. S; Kangueanne, P; Abraham, B.; Pennathur, G. Lett. Appl. Microbiol., 29, 66 1999.
  • A Low Cost RS–232C based Computer Interface. Senthil Kumar, K.; Laskhmi, B. S.; Gautam, P. Journal of Automatic Chemistry, 20, 189 1998.
  • Coordination Aggregation of Mesoaryl Substituted Porphyrins. Gautam, P.; Krishnan, V. Proceedings of the Indian National Academy of Sciences, 107, 412, 1994.
  • Internal Rotation in Auramine – O. Gautam, P.; Harriman, A. Journal of Chemical Society Faraday Transactions, 90, 697 1994
  • Temperature Dependence of the Exchange Coupling in Polyethylene Chain Biradicals Conclusion regarding the Mechanism of Coupling. Forbes, M. B. E.; Closs, G. L.; Calle, P; Pennathur Gautam J. Phys. Chem.,97, 3384 , 1993
  • Steady State and Time Resolved Direct Detection of Fullerene Triplets in Liquid Solution snd Glassy Matrices. Evidence of Dynamic Jahn–Teller Effect in Triplet C60 . Closs, G. L.; Gautam, P.; Zhang, D.; Krusic, P.; Hill, S. A.; Wasserman, E. J. Phys. Chem. 96, 5228 1993


  • Recepient of the UGC-CSIR Scholarship for Doctoral Research 1983
  • Recepient of UGC–BSR one time grant in 2012.
  • Indian National Science Academy Teachers Award 2012.

( Undergraduate Students who Carried out Projects in Our Group & Their Present Positions )

Name Year Present Position
Dr. T. Vatasla 1996 Assistant Professor , NCBS , Bangalore
Dr. M. Krishnan 1997 Assistant Professor, University of Zurich
Dr. M. J. Ananth 2000 Assistant Professor, South Western Medical Center, Dallas.
Dr. Sunil Laxman 2000 Principal Scientist , In-STEM, Bangalore.
Dr. Athi Narayanan 2002 Assistant Professor, IIT, Madras.
Dr. Ashwin Sai Narain 2003 Scientist , NCBS, Bangalore.
Dr. S. Krithivasan 2003 Assistant Professor, University of Okalhoma,U.S.A.
Dr. Siddarth Jhunjhunwala 2004 Assistant Professor, IISc, Bangalore


Professor, Centre for Biotechnology

Anna University, Chennai 600025


pgautam@annauniv.edu ,