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Department of Biotechnology Anna University

Adaikkalam Vellaichamy, Ph.D


Associate Professor, Centre for Biotechnology

Anna University, Chennai 600025
044 - 22358367

adai@annauniv.edu, adaiks98@yahoo.com








Education

Degree Year University
Ph D 1998 - 2002 National University of Singapore, Singapore
M. Tech. 1991 – 1993 Anna University, Chennai,India
M. Sc 1987 – 1989 Bharathidasan University, Trichy, India

Past Positions/ Research Areas

2010 – 2012 Assistant Member, Department of Nanomedicine, The Methodist Hospital Research Institute, Houston, USA
Co-Director, Proteomics Programmatic core, The Methodist Hospital Research Institute, Houston, USA
2008 – 2010 Post-doctoral Research Associate & IGB Fellow, Institute for Genomic biology, University of Illinois at Urbana Champaign, USA
2005 – 2008 Post-doctoral Research Fellow, Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, USA
2003 – 2005 Post-doctoral Fellow, Genome Institute of Singapore, Singapore
1993 – 1998 Scientist A (Biotechnology), Malladi Research Center, Malladi drugs & Pharmaceuticals Ltd., Chennai, India




OTHER RESPONSIBILITIES HELD

1. Faculty Advisor for M.Tech Biotechnology programme & Co-coordinator for M.Tech Biotech (JNU-DBT admissions).
2. Project Coordinator for all PGs in the Department.
3. Department Faculty Coordinator for NAAC & NIRF Committees
4. Department Faculty Coordinator for Entrepreneurship Development Cell, A.C.Tech.
5. Dy Coordinator & PI, AU-DBT BUILDER Programme

Grants at Anna University

Agency Area Year Grant Amount Role
DBT, New Delhi DBT-BUILDER Programme to AU 2014-2019 Rs. 10.56 Crore Dy Coordinator (PI of Proteomics facility: Rs 4.8 Cr)
DST-SERB Bacterial proteomics 2019-2020 Rs. 27.00 Lakhs total Joint PI (Rs. 7.01 Lakhs)
DST-SERB Genomics & Proteomics of Prostate Cancer 2020-2022 Rs. 55.00 Lakhs PI
DBT-CTEP, New Delhi Overseas Travel Grant 2016 Rs.1.01 Lakhs Recipient
CTDT, AU UG project 2018 Rs. 0.25 Lakhs Mentor
CTDT, AU UG project 2019 Rs. 0.25 Lakhs Mentor

Subjects Teaching

Courses Institution UG/PG/PhD
Applied Genomics and Proteomics Anna University PG/PhD
Advanced Technologies in Omics Sciences Anna University PG/PhD
Nanobiotechnology Anna University PG/PhD
Genomics and Proteomics Anna University UG
Protein Structure Function & Proteomics Anna University UG
Advanced Techniques in Biotechnology Anna University UG
Biochemistry Lab. Anna University UG
Molecular Biology Lab. Anna University UG
Bioprocess Practical-1 Lab Anna University UG


New courses introduced

• Advanced Genomics and Proteomics (PG)

• Proteomics and Mass-spectrometry (PG)

• Advanced Technologies in Omics Sciences (PG)



Existing Courses updated

• Bio-nanotechnology (PG)

• Genomics and Proteomics (UG)



Other Activities

• Faculty Coordinator for National Level Technical Symposium- “Biotechcellence (BTX)” held at Anna University, Chennai, March 2018, 2017 & 2016

• Doctoral Committee Member for MS, Ph.D Students at Anna University, PhD students from University of Madras, CLRI, and Vellore Institute of Technology.

• Supervisor for research projects (B.Tech, M. Tech, MS, Ph.D, and PDFs).

• Member of review committee & Viva-voce examinations for UG, PG student projects at the department.

• Conduct Demo/ workshop on MALDI-TOF MS and 2-D Gel electrophoresis as part of Technical symposia.






Research interests


• Proteomics

• Genomics and Metabolomics

• Biological Mass-spectrometry

• Cancer biology

• Biomarker Discovery


Membership


• American Society for Mass-spectrometry (ASMS)

• Human Proteome Organization (HUPO)

• Proteomics Society of India (PSI)




Grants at Anna University


Agency Area Year Grant Amount Role
DBT, New Delhi DBT-BUILDER Programme to AU 2014-2019 Rs. 10.56 Crore Dy Coordinator (PI of Proteomics facility: Rs 4.8 Cr)
DST-SERB Bacterial proteomics 2019-2020 Rs. 27.00 Lakhs total Joint PI (Rs. 7.01 Lakhs)
DST-SERB Genomics & Proteomics of Prostate Cancer 2020-2022 Rs. 55.00 Lakhs PI
DBT-CTEP, New Delhi Overseas Travel Grant 2016 Rs.1.01 Lakhs Recipient
CTDT, AU UG project 2018 Rs. 0.25 Lakhs Mentor
CTDT, AU UG project 2019 Rs. 0.25 Lakhs Mentor

Some of the Invited Talks Given


• “Mass Spectrometry based Proteomics of Prostate Cancer”- lecture towards the 2018-2019 special lecture series conducted by Department of Biochemistry, University of Madras. Lecture given on 27th September, 2018.

• “Integrated Omics-based approach for Biomarker Discovery”- talk at the international Cornea and Ocular Surface Symposium – SYNERGY at Sankara Nethralaya, Chennai. March 24-25, 2018

• “High throughput Omics Technologies in Nanomedicine” – talk at the International Workshop on Advanced Functional Nanomaterials (IWAN-4) held at Anna University, March 22-24, 2017.

• “Genomics and allied Omics Technologies” Invited talk at UGC refresher course for college teachers at Nanoscience centre, University of Madras, Chennai. 17th Nov. 2016.

• “Biomarker discovery through Proteomics and allied Omics Sciences” – talk at the Department of Bioinformatics, Bharathiyar University, Coimbatore, 28th June 2016.

• “Advances in Genomics, Proteomics and allied Omics Sciences” – talk in the UGC-CSIR coaching classes at CAS in Botany, University of Madras, Chennai, 26th May. 2014.

• “Technologies in Omics Sceinces” – talk at the TEQIP-II sponsored national symposium PANACEA’14 at BIT, Anna University, Trichy, 25th March 2014.

• “Comparative and Quatitative Proteomics” – talk in BRNS, DAE sponsored national seminar on Application of Proteomics in Clinical Biochemistry at Mepco Schlenk Engineering College, Sivakasi, TamilNadu, 28th Feb. 2014.




Some of the Workshops / Courses attended


• Faculty Development Program on “Digital & its Transformation” conducted by Cognizant, Chennai, 23rd Sep, 2017.

• FDTP on “Environmental Science & Engineering” conducted by Centre for Faculty Development at CEG, Anna University, 16-23, June 2017.

• FDP on “Entrepreneurship” organized by Programme Monitoring office – Innovation & Entrepreneurship Development Program, 24-26, Nov. 2016.

• Certificate course on Effective Patent Drafting, conducted by CIPR- Anna University & TamilNadu Technology Development and Promotion Centre (TNTDPC) 9-13, Nov. 2016.

• NAAC Awareness Seminar / Training on “Quality System in Higher Education”, organized by Internal Quality Assurance Cell (IQAC), Anna University, Chennai 29-30, Sep. 2016.

• Participated in the “Chennai Science Festival 2016” organized by the Science City on the theme “Disaster Management” at the Queen Marys College, Chennai, 26-29, Feb. 2016.

• Symposium on Research Methodology for Medical and Biomedical Scientists at National Institute of Pathology (NIP), CSIR, New Delhi, 20-24, April-2015.






Selected Publications


  • Kumar V.S. and Vellaichamy A. (2019) Sequence and structure-based characterization of ubiquitination sites in human and yeast proteins using Chou's sample formulation. Proteins. 87:646-657. Impact factor: 2.501
  • Selvaraj SM, Christina JJ, Gurumoorthy S, Gita BJ, and Vellaichamy A. (2019) Association of -757T>C polymorphism of C-reactive protein gene with chronic periodontitis of South Indian population. Inflamm Res. 68:347-349. Impact factor: 3.061
  • Sakamoto J, Godin B, Hu Y, Blanco E, Van de Ven A.L, Vellaichamy A, Murphy M.B., Francesca S.L, Schuenemeyer T, Given B, Meyn A, and M Ferrari. Nanomedicine handbook series (2015): Chapter – 49 in “Handbook of Clinical Nanomedicine: From Bench to Bedside”- published by Pan Stanford Publishing Pte. Ltd.
  • Wu X, Vellaichamy A, Wang D, Zamdborg L, Kelleher NL, Huber SC, Zhao Y. (2013). Differential lysine acetylation profiles of Erwinia amylovora strains revealed by proteomics. J Proteomics. 79:60-71. Impact factor: 3.87
  • Ateeq B, Vellaichamy A, Tomlins SA, Wang R, Cao Q, Lonigro RJ, Pienta KJ, Varambally S. (2012). Role of dutasteride in pre-clinical ETS fusion-positive prostate cancer models. Prostate. 72(14):1542-1549. Impact factor: 3.82
  • Tran JC, Zamdborg L, Ahlf DR, Lee JE, Catherman AD, Durbin KR, Tipton JD, Vellaichamy A, Kellie JF, Li M, Wu C, Sweet SM, Early BP, Siuti N, LeDuc RD, Compton PD, Thomas PM, Kelleher NL (2011). Mapping intact protein isoforms in discovery mode using top-down proteomics. Nature. 480:254-258. Impact factor: 40.14
  • Vellaichamy A, Tran JC, Catherman AD, Lee JE, Kellie JF, Sweet SM, Zamdborg L, Thomas PM, Ahlf DR, Durbin KR, Valaskovic GA, and Kelleher NL (2010). Size-Sorting Combined with Improved Nanocapillary-LC-MS for Identification of Intact Proteins up to 80 kDa. Anal. Chem. 82(4):1234-1244. Impact factor: 6.32
  • Vellaichamy A, Lin CY, Aye TT, Kunde KR, Nesvizhskii AI, Liu ET, and Sze SK (2010). A Chloroform-Assisted Protein Isolation Method Followed by Capillary NanoLC-MS Identify Estrogen-Regulated Proteins from MCF7 Cells. J Proteomics Bioinform. 3: 212-220. Impact factor: 1.57 (3.14 five years’)
  • Vellaichamy A, Dezso Z, JeBailey L, Chinnaiyan AM, Sreekumar A, Nesvizhskii A, Omenn GS, and Bugrim A (2010). Networking genes with proteins: finding relations between proteomic and gene expression datasets using topology of the global interaction network. PLOS ONE 5(6):e10936. Impact factor: 4.41
  • Kellie JF, Tran JC, Lee JE, Ahlf DR, Thomas HM, Ntai I, Catherman AD, Durbin KR, Zamdborg L, Vellaichamy A, Thomas PM, and Kelleher NL (2010). The Emerging Process of Top-Down Mass Spectrometry- Biomarkers, Protein-Therapeutics, and Achieving High Throughput. Mol. Biosyst. 6: 1-8. Impact factor: 3.83
  • Yu J, Yu J, Mani RS, Cao Q, Brenner CJ, Cao X, Wang GX, Wu L, Li J, Hu M, Gong Y, Cheng H, Laxman B, Vellaichamy A, Shankar S, Li Y, Dhanasekaran SM, Morey R, Barrette T, Lonigro RJ, Tomlins SA, Varambally S, Qin ZS, Chinnaiyan AM (2010). An Integrated Network of Androgen Receptor and TMPRSS2-ERG Gene Fusion in Prostate Cancer Progression. Cancer Cell 17(5):443-454. Impact factor: 26.93
  • Vellaichamy A, Sreekumar A, Rajendiran T, Yu J, Varambally S, Li Y, Omenn GS, Chinnaiyan AM, and Nesvizhskii AI (2009). Proteomic Interrogation of Androgen Action in Prostate Cancer Cells Reveals Roles of Aminoacyl tRNA Synthetases. PLOS ONE. 4(9):e7075. Impact factor: 4.35
  • Lee JE, Kellie JF, Tran JC, Tipton JD, Catherman AC, Thomas HM, Ahlf DR, Durbin KR, Vellaichamy A, Ntai I, Hendrickson CL, Emmett MR, Marshall AG, and Kelleher NL (2009). A Robust 2-Dimensional Separation for Top-Down Tandem Mass Spectrometry of the Low Mass Proteome. J Am Soc Mass Spectrom. 20(12):2183-2191. Impact factor: 3.39
  • Anandaraj B, Vellaichamy A, Kachman M, Selvamanikandan A, Pegu S, and Murugan V. (2009). Co-production of two new peptide antibiotics by a bacterial isolate Paenibacillus alvei NP75. Biochem Biophys Res Commun. 379:179-85. Impact factor: 2.83


Participation in International Conferences


  • Second Global Innovation Summit by Shimadzu, held in Kyoto, Japan, JUL 2019
  • 67th American Society for Mass Spectrometry conference on Mass Spectrometry and Allied Topics, held in Atlanta, Georgia, USA, Jun. 2019.
  • International Cornea and Ocular Surface Symposium – SYNERGY at Sankara Nethralaya, Chennai. March, 2018
  • International Conference on Translational Medicine & Imaging (ICTMI) – (2017) held at V.I.T. Vellore, Aug. 2017
  • 64th ASMS conference on Mass Spectrometry and Allied Topics, held in San Antonio, Texas, USA, Jun. 2016.
  • 7th Annual Meeting and International conference by Proteomics Society of India, held at V.I.T. Vellore, Nov. 2015.
  • 6th Annual Meeting and International conference by Proteomics Society of India, held at I.I.T. Bombay, Nov. 2014.
  • 5th Annual Meeting and International conference by Proteomics Society of India, held at I.I.Sc. Bangalore, Nov. 2013
  • 60th ASMS Conference on Mass Spectrometry and Allied Topics held in Vancouver, BC, Canada, May 2012.




Awards and Honors


  • Awarded Assistant Member position at The Methodist Hospital Res. Institute, USA 2010
  • Named as an IGB Fellow at the Institute for Genomic Biology, University of Illinois at Urbana –Champaign (UIUC), USA 2008
  • Research Scholarship award for Ph. D. by National University of Singapore (NUS) 1998
  • Graduate Aptitude Test in Engineering (GATE) Scholarship award for M. Tech.,by Department of Biotechnology, Government of India 1991
  • Medal for academic proficiency in college during M. Sc. 1989






Contact


Associate Professor, Centre for Biotechnology

Anna University, Chennai 600025

adai@annauniv.edu

044 - 22358367

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