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Department of Biotechnology Anna University

Adaikkalam Vellaichamy, Ph.D


Associate Professor, Centre for Biotechnology

Anna University, Chennai 600025
044 - 22358367

adai@annauniv.edu, adaiks98@yahoo.com








Education

Degree Year University
Ph D 2002 National University of Singapore, Singapore
M. Tech. 1993 Anna University, Chennai,

Past Positions/ Research Areas

2010 – 2012 Assistant Member, Department of Nanomedicine, The Methodist Hospital Research Institute, Houston, USA
Co-Director, Proteomics Programmatic core, The Methodist Hospital Research Institute, Houston, USA
2008 – 2010 Post-doctoral Research Associate & IGB Fellow, Institute for Genomic biology, University of Illinois at Urbana Champaign, USA
2005 – 2008 Post-doctoral Research Fellow, Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, USA
2003 – 2005 Post-doctoral Fellow, Genome Institute of Singapore, Singapore
1993 – 1998 Scientist A (Biotechnology), Malladi Research Center, Malladi drugs & Pharmaceuticals Ltd., Chennai, India








Research interests


• Proteomics and allied Omics Technologies

• Biological Mass-spectrometry

• Biomarker Discovery for human diseases

• Cancer biology

• Bio-nanotechnology


Membership


• American Society for Mass-spectrometry (ASMS)

• Human Proteome Organization (HUPO)

• Proteomics Society of India (PSI)





Selected Publications


  • Wu X, Vellaichamy A, Wang D, Zamdborg L, Kelleher NL, Huber SC, Zhao Y. (2013). Differential lysine acetylation profiles of Erwinia amylovora strains revealed by proteomics. J Proteomics. 79:60-71. Impact factor: 3.87
  • Ateeq B, Vellaichamy A, Tomlins SA, Wang R, Cao Q, Lonigro RJ, Pienta KJ, Varambally S. (2012). Role of dutasteride in pre-clinical ETS fusion-positive prostate cancer models. Prostate. 72(14):1542-1549. Impact factor: 3.82
  • Tran JC, Zamdborg L, Ahlf DR, Lee JE, Catherman AD, Durbin KR, Tipton JD, Vellaichamy A, Kellie JF, Li M, Wu C, Sweet SM, Early BP, Siuti N, LeDuc RD, Compton PD, Thomas PM, Kelleher NL (2011). Mapping intact protein isoforms in discovery mode using top-down proteomics. Nature. 480:254-258. Impact factor: 40.14
  • Vellaichamy A, Tran JC, Catherman AD, Lee JE, Kellie JF, Sweet SM, Zamdborg L, Thomas PM, Ahlf DR, Durbin KR, Valaskovic GA, and Kelleher NL (2010). Size-Sorting Combined with Improved Nanocapillary-LC-MS for Identification of Intact Proteins up to 80 kDa. Anal. Chem. 82(4):1234-1244. Impact factor: 6.32
  • Vellaichamy A, Lin CY, Aye TT, Kunde KR, Nesvizhskii AI, Liu ET, and Sze SK (2010). A Chloroform-Assisted Protein Isolation Method Followed by Capillary NanoLC-MS Identify Estrogen-Regulated Proteins from MCF7 Cells. J Proteomics Bioinform. 3: 212-220. Impact factor: 1.57 (3.14 five years’)
  • Vellaichamy A, Dezso Z, JeBailey L, Chinnaiyan AM, Sreekumar A, Nesvizhskii A, Omenn GS, and Bugrim A (2010). Networking genes with proteins: finding relations between proteomic and gene expression datasets using topology of the global interaction network. PLOS ONE 5(6):e10936. Impact factor: 4.41
  • Kellie JF, Tran JC, Lee JE, Ahlf DR, Thomas HM, Ntai I, Catherman AD, Durbin KR, Zamdborg L, Vellaichamy A, Thomas PM, and Kelleher NL (2010). The Emerging Process of Top-Down Mass Spectrometry- Biomarkers, Protein-Therapeutics, and Achieving High Throughput. Mol. Biosyst. 6: 1-8. Impact factor: 3.83
  • Yu J, Yu J, Mani RS, Cao Q, Brenner CJ, Cao X, Wang GX, Wu L, Li J, Hu M, Gong Y, Cheng H, Laxman B, Vellaichamy A, Shankar S, Li Y, Dhanasekaran SM, Morey R, Barrette T, Lonigro RJ, Tomlins SA, Varambally S, Qin ZS, Chinnaiyan AM (2010). An Integrated Network of Androgen Receptor and TMPRSS2-ERG Gene Fusion in Prostate Cancer Progression. Cancer Cell 17(5):443-454. Impact factor: 26.93
  • Vellaichamy A, Sreekumar A, Rajendiran T, Yu J, Varambally S, Li Y, Omenn GS, Chinnaiyan AM, and Nesvizhskii AI (2009). Proteomic Interrogation of Androgen Action in Prostate Cancer Cells Reveals Roles of Aminoacyl tRNA Synthetases. PLOS ONE. 4(9):e7075. Impact factor: 4.35
  • Lee JE, Kellie JF, Tran JC, Tipton JD, Catherman AC, Thomas HM, Ahlf DR, Durbin KR, Vellaichamy A, Ntai I, Hendrickson CL, Emmett MR, Marshall AG, and Kelleher NL (2009). A Robust 2-Dimensional Separation for Top-Down Tandem Mass Spectrometry of the Low Mass Proteome. J Am Soc Mass Spectrom. 20(12):2183-2191. Impact factor: 3.39
  • Anandaraj B, Vellaichamy A, Kachman M, Selvamanikandan A, Pegu S, and Murugan V. (2009). Co-production of two new peptide antibiotics by a bacterial isolate Paenibacillus alvei NP75. Biochem Biophys Res Commun. 379:179-85. Impact factor: 2.83


Participation in International Conferences


  • 64th ASMS conference on Mass Spectrometry and Allied Topics, held in San Antonio, Texas, USA, Jun. 2016.
  • 7th Annual Meeting and International conference by Proteomics Society of India, held at V.I.T. Vellore, Nov. 2015.
  • 6th Annual Meeting and International conference by Proteomics Society of India, held at I.I.T. Bombay, Nov. 2014.
  • 5th Annual Meeting and International conference by Proteomics Society of India, held at I.I.Sc. Bangalore, Nov. 2013
  • 60th ASMS Conference on Mass Spectrometry and Allied Topics held in Vancouver, BC, Canada, May 2012.




Awards and Honors


  • Awarded Assistant Member position at The Methodist Hospital Res. Institute, USA
  • IGB Fellow at the Institute for Genomic Biology, University of Illinois at Urbana – Champaign, USA
  • Post-doctoral Fellowship award at University of Michigan, Ann Arbor, USA
  • Post-doctoral Fellowship award at Genome Institute of Singapore, Singapore
  • Research Scholarship award for Ph. D. by National University of Singapore, Singapore
  • Graduate Aptitude Test in Engineering (GATE) Scholarship award for M. Tech. by Department of Biotechnology, Government of India






Contact


Associate Professor, Centre for Biotechnology

Anna University, Chennai 600025

adai@annauniv.edu

044 - 22358367

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